Phthalic definition, of or derived from phthalic acid. Grind 15 g of phthalic anhydride and 22 g. of resorcinol together and transfer the mixture to a conical flask. The total concentrations of terephthalic acid and phthalic acid were higher in summer and winter, but lower in spring and autumn.sentence dictionary TCC’s phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasticizers, and insecticides. 20:790. MDL number MFCD00005918. MDL number MFCD00002467. C.A.S.E. It is presently obtained by catalytic oxidation of ortho–xylene or naphthalene. Molecular Weight 148.12 . FTIR confirmed the esterification of glycerol by the acid for all the polymers. Phthalic anhydride. 230°C, yield about 92%.2,3 Note:Concentrated ammonia solution can be used in place of urea. … Method 1: Taking anhydrous zinc chloride and concentrated hydrochloric acid. Phthalic anhydride ACS reagent, ≥99% CAS Number 85-44-9. … Principal markets are construction, marine and transportation. (APF = 10) Any air-purifying full-facepiece respirator equipped with an N95, R95, or P95 filter. Phthalic anhydride is a precursor to a variety of reagents useful in organic synthesis. Weigh out rapidly 7 g. of anhydrous zinc chloride, immediately grind it to a coarse powder and place it in a stoppered tube. Phthalic anhydride is also used as a precursor of anthraquinone, phthalein, rhodamine, phthalocyanine, fluorescein, and xanthene dyes. Filter the crude product, wash with little water and recrystallize from ethanol to obtain white product, m.p. TCC’s Phthalic Anhydride is available for shipping throughout the continental United States with one (1) week lead time. 4. The following filters may also be used: N99, R99, P99, N100, R100, P100. It will, for example, react readily with alcohols on warming, yielding initially the “half-esters” of phthalic acid, the alkyl hydrogen phthalates (XII). In: Hygienic guide series. Phthalic anhydride is the anhydride of phthalic acid. Click here for information on selection of N, R, or P filters.*/. Strictly Necessary Cookie should be enabled at all times so that we can save your preferences for cookie settings. The product is phenolphthalein. The para isomer, terephthalic acid, is also used to make polymers—namely, polyesters (see below Derivatives of carboxylic acids: Carboxylic esters). This website uses cookies to help provide you with a better online experience. 3. NACRES NA.21 Please call (401) 360-2800 for details. Reactions of Phthalic Anhydride. This colorless solid is an important industrial chemical, especially for the large–scale production of plasticizers for plastics. Click here for information on selection of N, R, or P filters. It is slightly soluble in hot water, hydrolysing to Phthalic Acid. Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus. AIHA [1967]. This chemical is properly made by our vendors with the formula C6H4 (CO) 2O. ], inhalation, ingestion, skin and/or eye contact, irritation eyes, skin, upper respiratory system; conjunctivitis; nasal ulcer bleeding; bronchitis, bronchial asthma; dermatitis; In Animals: liver, kidney damage, Eyes, skin, respiratory system, liver, kidneys, Centers for Disease Control and Prevention. Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and readily available. Phthalic anhydride reacts violently with CuO at elevated temperatures [Park, Chang-Man, Richard J. 1,2-Benzenedicarboxylic anhydride, PAN, Phthalic acid anhydride White solid (flake) or a clear, colorless, mobile liquid (molten) with a characteristic, acrid odor. The second largest outlet for PA is in unsaturated polyester resins (UPR) which are usually blended with glass fibers to produce fiberglass-reinforced plastics. 1972]. Phthalic acid is produced by the catalytic oxidation of naphthalene or ortho-xylene directly to phthalic anhydride and a subsequent hydrolysis of the anhydride. This colorless solid is an important industrial chemical, especially for the large–scale production of plasticizers for plastics. Phthalic anhydride. Strong oxidizers, water One of the main uses of phthalic anhydride is the production of “phthalate” plasticizers such as Vestinol 9 DINP (DiIsoNonyl Phthalate) which are used to produce flexible PVC (Vinyl) products. (Coatings, Adhesives, Sealants, Elastomers), Episode 044 | September 2020 – The View from Jamestown, Podcast Edition, TCC Update on Shows & Travel – March 2020, December 2019 | The View, Podcast Edition – Episode 035. Phthalic anhydride can also be prepared from phthalic acid. Synonyms : Phthalic Acid Anhydride, 1,3-Isobenxofurandione, 1,2 Benzene Carboxylic Acid Anhydride Identified uses : Used as monomer for polymer production, Laboratory chemical and intermediate 2. Empirical Formula (Hill Notation) C 8 H 4 O 3. 5.2.). Because both these methods convert the collected phthalic anhydride to, and analyze as, phthalic acid, they are susceptible to positive interference from any phthalic acid originally present in the air. Click here for information on selection of N, R, or P filters. *, Up to 60 mg/m3: (APF = 10) Any particulate respirator equipped with an N95, R95, or P95 filter (including N95, R95, and P95 filtering facepieces) except quarter-mask respirators. Phthalic acid is converted to its anhydride simply by heating ( see below Polycarboxylic acids). Remove the flame and allow cooling. Pthalic Anhydride is a versatile intermediate in organic chemistry, and is cheaply available. Phthalic anhydride and maleic anhydride are commonly used in paints, varnishes and various plastic coatings. 1972]. It reacts with strong oxidants and responds violently when heated with copper oxide or sodium nitrite, to cause an explosion hazard. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. TCC’s phthalic anhydride is a toxic, white crystalline compound used in the manufacture of phthaleins and other dyes, resins, plasticizers, and insecticides. Therefore, the intermediate product is phthalic acid and final products are phthalic anhydride, carbon dioxide and water. Phthalic anhydride is widely used in industry for the production of certain dyes. …aromatic dicarboxylic acids are called phthalic, isophthalic, and terephthalic acid, for the ortho, meta, and para isomers, respectively. When separating the phthalic anhydride from production by products such as o–xylene in water, or maleic anhydride, a series of “switch condensers” is required. Three glycerol:phthalic acid molar ratio used for the bulk polymerization were: 2:2; 2:3 and 2:4. Important derivatives include phthalimide and its many derivatives. White solid (flake) or a clear, colorless, mobile liquid (molten) with a characteristic, acrid odor. The zinc chloride should not be exposed to the air. Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), National Institute for Occupational Safety and Health, A – NIOSH Potential Occupational Carcinogens, B – Thirteen OSHA-Regulated Carcinogens, D – Substances with No Established RELs, E – OSHA Respirator Requirements for Selected Chemicals, G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect, Type C & CE – Definitions for Type C and Type CE Respirators, U.S. Department of Health & Human Services. In 2000, the worldwide production volume was estimated to be about 3 million tonnes per year. 3rd ed., Volumes 1-26. (1) Phthalic anhydride is used in the synthesis of primary amines, the agricultural fungicide phaltan, and thalidomide. H 2 S O 4 . carboxylic acid: Aromatic acids. DSC indicated no crystallinity, although the XRD plots indicate a very incipient crystallinity for the polymers containing higher amounts of phthalic anhydride. The diethyl and dihexyl esters are very widely used for this purpose. & Ind. Step 2: Preparat… It is the anhydride of phthalic acid. PHTAN) is the anhydride of phthalic acid. Biofax [1970]. However, the pr oducts of the r eaction can be comple x mainl y due to the fact that both phthalic anhydride and ethylenediamine, the (APF = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. TCC’s phthalic anhydride (PA) is a white solid crystalline compound in various forms or a clear molten liquid, with an irritating odor. Kirk-Othmer Encyclopedia of Chemical Technology. Heat the flask on an oil bath to 180° (internal temperature). These include, but are not limited to Wire & Cable applications, coated fabrics, roofing membranes and swimming pool liners. Phthalic anhydride is the anhydride of phthalic acid. It is an isomer of isophthalic acid and terephthalic acid. See more. Go To: Top, References, Notes Data compilation copyrightby the U.S. Secretary of Commerce on behalf of the U.S.A.All rights reserved. Important additional information about respirator selection, 1,2-Benzenedicarboxylic anhydride, PAN, Phthalic acid anhydride. Phthalic Anhydride. Am Ind Hyg Assoc J 28:395-398. Diseases due to phthalic acid and its compounds. Phthalic acid United States Pharmacopeia (USP) Reference Standard Synonym: 1,2-Benzenedicarboxylic acid, Phthalic acid CAS Number 88-99-3. Baader EW [1955]. & Ind. Phthalic anhydride has another major use in the production of polyester resins and other minor uses in the production of alkyd resins used in paints and lacquers, certain guys, insect repellents, and urethane polyester polyols. In acidic medium phenolphthalein is colourless. Phthalic anhydride is presently obtained by catalytic oxidation of ortho–xylene or naphthalene. Molecular Weight 166.13 . Undergoes exothmeric nitration with fuming nitric acid-sulfuric acid and may give mixtures of the potentially explosive phthaloyl nitrates or nitrites or their nitro derivatives [Chem. A well-known application of this reactivity is the preparation of the anthroquinone dye quinizarin by reaction with para–chlorophenol followed by hydrolysis of the chloride. Northbrook, IL: Biofax Industrial Bio-Test Laboratories, Inc. 5. The third largest outlet is PA-based alkyd resins that are used in solvent-based coatings for architectural, machinery, furniture and fixture applications. Heat the flask on an oil bath/sand bath/heating mantle at 130-135°C till the contents melts, froth up and become solid. Phthalic acid, when found in tissues or biofluids arises from exposure to these phthalate products. CDC twenty four seven. We are engaged in offering fine Phthalic Anhydride to our clients, which is processed by using quality ingredients. 20:790. 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